Fibrin Associated Epstein–Barr Virus Positive Large B Cell Lymphoma as a Complication of a Repaired Thoraco-abdominal Aortic Aneurysm

Abstract

Background Malignancies involving the aorta are extremely rare. Case report A 62 year old man with a history of open repair of a thoracic aortic aneurysm developed new visceral aneurysms and an anastomotic pseudoaneurysm. Fludeoxyglucose positron emission tomography/computed tomography, performed for suspicion of graft infection, found abnormal uptake around the bypass, the visceral aneurysms, and the femoral arteries. The patient was treated by embolisation of the visceral aneurysms and a thoracic endovascular aortic repair. Several bleeding complications occurred, and the patient died. Post-mortem revealed a fibrin associated Epstein–Barr virus positive diffuse large B cell lymphoma. Conclusion Patients with aortic aneurysms can develop malignancies including fibrin associated lymphoma. Clinical manifestations may be similar to those of an infectious process; timely diagnosis is uncommon.