Legume consumption increase adiponectin concentrations among type 2 diabetic patients: A randomized crossover clinical trial.

Abstract

BACKGROUND AND OBJECTIVE\nThis randomized crossover clinical trial investigated the effects of substituting legumes for meat consumption in the therapeutic lifestyle change (TLC) diet on leptin and adiponectin concentrations among type 2 diabetic patients.\n\n\nMATERIAL AND METHODS\nThirty-one type 2 diabetic patients (24 women, age: 58.1±6.0 years) were randomly assigned to groups designated to consume a legume-free TLC diet or a legume-based TLC diet for 8 weeks. Both diets were similar except for the replacement of two servings of red meat with legumes 3 days per week in the legume-based TLC group. Leptin and adiponectin concentrations were measured at baseline and after the 8-week intervention.\n\n\nRESULTS\nThe legume-based TLC diet significantly increased adiponectin concentrations in comparison with the legume-free TLC diet. There was no significant change in leptin concentrations after both intervention diets.\n\n\nCONCLUSIONS\nLegumes increased serum adiponectin concentrations in type 2 diabetic patients. Registration number: IRCT201202251640N7.