Impact of exposure to noise on the risk of hypertension: A systematic review and meta-analysis of cohort studies.

Abstract

OBJECTIVE\nWe aimed to synthesize available cohorts about the relationship between various types of noise and hypertension, and to explore the potential dose-response relationship between them in an updated meta-analysis.\n\n\nMETHODS\nPubMed and Embase were searched through October 2019 to identify cohort studies that met predetermined inclusion criteria. A random-effects model was used to combine the results of included studies. Dose-response meta-analysis was conducted to examine the potential dose-response relationship.\n\n\nRESULTS\nEleven cohort studies involving 224,829 participants were included in this systematic review. Pooled result showed that living or working in environment with noise exposure was significantly associated with increased risk of hypertension (RR: 1.18; 95% CI: 1.06 to 1.32), with low heterogeneity (P\xa0=\xa00.098, I2\xa0=\xa042.1%). We found no evidence of a nonlinear association of elevated noise with hypertension risk (P\xa0=\xa00.443). The summary risk ratio of hypertension for an increment of per 10\xa0dB(A) of noise was 1.13 (95% CI: 0.99 to 1.28), with moderate heterogeneity (P\xa0=\xa00.003, I2\xa0=\xa072.1%).\n\n\nCONCLUSIONS\nIntegrated evidence from cohort studies supports the hypothesis that exposure to noise may be a risk factor of hypertension.