ID: 3524883 NONCONTACT MAGNETICALLY CONTROLLED CAPSULE ENDOSCOPY FOR INFECTION-FREE GASTRIC EXAMINATION DURING THE COVID-19 PANDEMIC: A PILOT, OPEN-LABEL, RANDOMIZED TRIAL

Abstract

FRIDAY, MAY 21, 2021 Clinical Endoscopic Practice 2 Lecture ID: 3524883 NONCONTACT MAGNETICALLY CONTROLLED CAPSULE ENDOSCOPY FOR INFECTION-FREE GASTRIC EXAMINATION DURING THE COVID-19 PANDEMIC: A PILOT, OPEN-LABEL, RANDOMIZED TRIAL Jia-Hui Zhu*, Jun Pan, Xiao-Nan Xu, Zhuan Liao Introduction: Endoscopists have been at increased risk because of the direct contact with patients during coronavirus disease 2019 (COVID-19) pandemic. Patients have been faced with the challenge to the diagnosis and monitoring of gastrointestinal cancer and digestive diseases timely due to the adjustment of endoscopy department. Herein, we developed a novel noncontact magnetically controlled capsule endoscopy (ncMCE) system based on telemedicine (Figure). In the current study, we aimed to evaluate the feasibility and safety of ncMCE for gastric examination. Methods: Patients were randomly assigned to groups that received ncMCE or MCE in AB50 GASTROINTESTINAL ENDOSCOPY Volume 93, No. 6S : 2021 a 1:1 ratio from March 26th to April 26th. Primary endpoints were feasibility assessed by completion rate (CR) and safety based on the occurrence of adverse events including infection. Secondary endpoints included maneuverability of endoscopists, pre-procedure perception and post-procedure satisfaction of patients, gastric examination time (GET) and diagnostic yield (DY). Results: Forty patients were enrolled with 100% CR in both groups without any adverse events. Neither the endoscopist nor the patients were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within 14 days after the gastric examination. There were no significant differences in maneuverability (19.3 vs. 20.0, P Z 0.179), pre-procedure perception (9 vs. 9, P Z 0.626) and post-procedure satisfaction (45 vs. 44, P Z 0.999) and DY (20% vs. 30%, PZ 0.465). GET of ncMCE group was slightly longer than MCE group (12.3 min vs. 7.2 min, PZ0.003) (Table). Discussion: The ncMCE is a feasible and safe diagnostic modality for gastric examination during the COVID-19 pandemic, which protects both medical staff and patients from COVID-19 infection while providing essential endoscopy service.