International journal of cardiology | 2019
Percutaneous haemodynamic and renal support in patients presenting with decompensated heart failure: A multi-centre efficacy study using the Reitan Catheter Pump (RCP).
Abstract
BACKGROUND\nWorsening heart failure complicated by congestion, hypotension, and renal dysfunction is difficult to manage, increasingly common and predicts a poor outcome. Novel therapies are required to facilitate diuresis and implementation of disease-modifying interventions in preparation for hospital discharge. Accordingly, we investigated the haemodynamic and renal effects of the Reitan Catheter Pump (RCP) percutaneous support device in patients admitted with decompensated heart failure (DHF).\n\n\nMETHODS\nThis was a prospective observational study of 20 patients admitted with DHF, ejection fraction\u202f<\u202f30%, and Cardiac index (CI)\u202f<\u202f2.1\u202fL/min/m2 in need of inotropic/mechanical support.\n\n\nRESULTS\nPatients underwent RCP support for a mean of 18.3 (±6.3) hours. The RCP increased CI from 1.84\u202fL/min/m2 (±0.27), to 2.41\u202fL/min/m2 (±0.45, p\u202f=\u202f0.04), increased urine output (71\u202fmL/h (±65) to 227\u202fml/h (±179) (p\u202f=\u202f0.006) with a concomitant reduction in serum creatinine (188\u202fμmol/L (±87) to 161\u202fμmol/L (±78) (p\u202f=\u202f0.0007). There were no clinically significant haemolysis, vascular injury, or thrombo-embolic complications.\n\n\nCONCLUSIONS\nFor patients admitted with DHF, the RCP improves cardiac index, diuresis and renal function without causing important complications.