JAAD Case Reports | 2019
Successful treatment of multinucleate cell angiohistiocytoma with fractionated ablative CO2 laser
Abstract
IPL: intense pulsed light MCAH: multinucleate cell angiohistiocytoma PDL: pulsed dye laser INTRODUCTION Multinucleate cell angiohistiocytoma (MCAH) is a rare and benign fibrohistiocytic and vascular proliferation. MCAH is characterized by wellcircumscribed red-brown dome-shaped papules often presenting on the hands, wrists, face, and legs with a higher prevalence in women. Lesions are composed of proliferation of dilated capillaries and small vessels in the papillary to mid dermis, fibrous stroma with thickened collagen bundles, and presence of multinucleated giant cells. The overlying epidermis may be normal or hyperplastic. MCAH lesions progress slowly, but spontaneous resolution is uncommon. Treatment modalities used for MCAH include topical or intralesional corticosteroids, surgical excision, cryosurgery, and laser therapy, and lesions are often refractory to treatment. Ablative CO2 laser and vascular selective lasers including argon and pulsed dye laser (PDL), and intense pulsed light (IPL) have been used for treatment of MCAH. Fractionated ablative CO2 laser combines the ablative properties with the rapid wound healing; hence, MCAH patients may benefit from treatment with fractionated ablative CO2 laser. Here we describe a patient with MCAH successfully treated with fractionated ablative CO2 laser.