Journal of Dental Sciences | 2021
Cryotherapy is effective for treatment of oral verrucous hyperplasia – Case report
Abstract
tps://doi.org/10.1016/j.jds.2020.12. 91-7902/a 2020Association for Denta e CC BY-NC-ND license (http://creati Oral verrucous hyperplasia (OVH) is a benign tumor-like lesion characterized by the outward growth of oral stratified squamous epithelium with verrucous surface. Our previous studies demonstrated that topical 5aminolevulinic acid-mediated photodynamic therapy and cryogun (Brymill Corp., Ellington, CT, USA) cryotherapy are very effective for treatment of OVH and oral leukoplakia lesions, respectively. Here, we presented an OVH lesion at the left buccal mucosa of a 29-year-old male patient, which was effectively treated to complete regression by one treatment of cryotherapy. This 29-year-old male patient came to our oral mucosal disease clinic for treatment of a tumor at the left buccal mucosa for 3 months. Oral examination revealed a painless elevated verrucous lesion measuring 3.0 1.5 0.8 cm at the left buccal mucosa (Fig. 1A). The patient had betel quid chewing (approximately 20 betel quids per day) and smoking habits (approximately 1.5 packs of cigarettes per day) for 10 years. Under the suspicion of a squamous cell carcinoma, the patient was referred to an oral and maxillofacial surgeon for doing a biopsy. The biopsy report issued one week later showed an OVH lesion. Because the patient refused to do surgery for excision of the OVH lesion, he finally decided to receive cryotherapy for removal of the OVH lesion. After obtaining the signed informed consent, the cryotherapy