Evaluating the Correlation and Performance of PROMIS to SRS Questionnaires in Adult and Pediatric Spinal Deformity Patients.

Abstract

STUDY DESIGN\nRetrospective cross-sectional cohort analysis.\n\n\nOBJECTIVES\n1) To assess the correlation of Patient-Reported Outcomes Management Information System (PROMIS) domains with SRS-22r/SRS-30 domains in all scoliosis patients; 2) to assess the correlation of PROMIS domains with SRS-30 domains in adult scoliosis patients; 3) to assess the correlation of PROMIS domains with SRS-22r/SRS-30 domains in pediatric scoliosis patients; and 4) to assess ceiling and floor effects of PROMIS and SRS-22r/SRS-30 domains. Studies evaluating correlations between PROMIS and a number of legacy PRO tools have been conducted. To our knowledge, no literature exists examining the correlation of PROMIS and SRS questionnaires in adult and pediatric spinal deformity patients.\n\n\nMETHODS\nOutpatient visits from July 2015 to December 2017 with concurrent PROMIS and SRS questionnaires were analyzed. Pediatric patients completed the SRS-22r, whereas adults completed the SRS-30. PROMIS measured Physical Function/Mobility, Pain Interference, and Depression domains. Spearman correlation coefficients (ρ) were calculated. Ceiling and floor effects were calculated and compared.\n\n\nRESULTS\n227 (164 adult; 64 pediatric) patient visits representing 173 patients were included. Moderate to strong correlation existed between PROMIS Physical Function/Mobility and SRS Function/Activity (F/A) domains (ρ, range 0.59-0.84; p < .001). PROMIS Pain Interference and SRS Pain domains showed strong-moderate to strong correlation (ρ, range -0.68 to -0.83; p < .001). PROMIS Depression and SRS Mental Health (MH) domains demonstrated strong-moderate to strong correlation (ρ, range -0.67 to -0.80; p < .001). Ceiling and floor effects were all less in PROMIS domains (range, 0.44% to 0.88%) compared with SRS domains (range, 0.88% to 17.62%).\n\n\nCONCLUSIONS\nPROMIS Physical Function/Mobility, Pain Interference, and Depression domains correlate well with SRS F/A, Pain, and MH. SRS SI/A and Satisfaction are not as well captured. PROMIS showed better ceiling and floor effects than SRS.\n\n\nLEVEL OF EVIDENCE\nLevel III.