Analysis of immune responses to attenuated alcelaphine herpesvirus 1 formulated with and without adjuvant

Abstract

Highlights • MCF vaccine was tested with and without adjuvant and containing inactivated virus.• Adjuvant was required for optimal virus neutralising antibody responses.• Storage of AlHV-1 with Emulsigen adjuvant significantly reduced virus viability.• Vaccination with adjuvant-inactivated AlHV-1 did not reduce antibody responses.