Prostatic Artery Embolization-Anatomic Predictors of Technical Outcomes.

Abstract

PURPOSE\nTo determine if cone-beam CT and digital subtraction angiography analysis of pelvic arterial anatomy has predictive value for radiation exposure and technical success of prostatic artery embolization (PAE).\n\n\nMATERIALS AND METHODS\nThis prospective, nonrandomized, single-center study included 104 consecutive patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia. Cone-beam CT was performed in 160/208 (76.9%) hemipelves to determine prostatic artery (PA) origin. Classification of pelvic arterial tortuosity was possible in 73/104 (70.2%) patients. Learning curves of 2 interventionalists who performed 86.5% of PAEs were analyzed.\n\n\nRESULTS\nTortuosity of pelvic arteries was classified as mild in 25 (34.2%) patients median age 64 years, moderate in 40 (54.8%) patients median age 69 years, and severe in 8 (11.0%) patients median age 70 years (mild vs moderate, P\xa0= .002; mild vs severe, P\xa0= .019); median fluoroscopy times were 24, 36, and 46 minutes (P\xa0= .008, P\xa0= .023); median contrast volumes were 105, 122.5, and 142 mL (P\xa0= .029, P\xa0= .064); and bilateral PAE rates were 84.0%, 77.5%, and 62.5% (P\xa0= .437), respectively. PA origin from superior vesical artery was most frequent (27.5%) and showed higher dose area product (median 402.4 vs 218 Gy ∙ cm2, P\xa0= .033) and fluoroscopy time (median 42.5 vs 27 min, P\xa0= .01) compared with PA origin from obturator artery, which was least frequent. Interventionalist experience revealed significant impact on procedure times (median 159 vs 130 min, P\xa0= .006).\n\n\nCONCLUSIONS\nTortuosity of pelvic arteries was more frequent in older patients and predicted worse technical outcomes of PAE. PA origin from obturator artery was associated with lower DAP and fluoroscopy time, especially compared with PA origin from superior vesical artery. Interventionalist experience showed significant influence on technical outcome.