Molecular cell | 2021
Come one, come all? Re-evaluating RNA polymerase II pre-initiation complex assembly using single-molecule microscopy.
Abstract
Complementary papers by Nguyen et\xa0al. (2021) and Baek et\xa0al. (2021) track the assembly of the pre-initiation complexes at gene promoters using single-molecule microscopy, revealing dynamic spatiotemporal regulation of transcription initiation.