Effects of Euterpe edulis Martius on inflammatory responses to high-intensity intermittent exercise: Crossover randomized trial.

Abstract

OBJECTIVE\nHigh-intensity intermittent exercise (HIIE) may enhance the antiinflammatory status. The juçara fruit juice (JFJ) has well-established antioxidant and antiinflammatory properties. This study investigated the effect of JFJ consumption on the inflammatory response to HIIE in physically active subjects.\n\n\nMETHODS\nIn a randomized crossover design, 15 men were assigned to drink 250 mL of either JFJ or water (control) 1 h before a cycling HIIE session (seven sets of 60 s at 100% peak power output; 75 s recovery between sets). Blood samples were obtained before and at 0, 30, and 60 min post-HIIE, and the serum was analyzed for interleukin (IL)-6, IL-1β, IL-8, IL-10, tumor necrosis factor-α, and cortisol.\n\n\nRESULTS\nAfter HIIE, the IL-6 levels were higher than baseline (percent change) at 30 min (P\xa0=\xa00.041) and 60 min (P\xa0=\xa00.038) for the control, but were unaffected by JFJ. IL-10 was higher in the JFJ group than in the control at 30 min (d\xa0=\xa0‒0.63). Tumor necrosis factor-α was lower than baseline at 30 min for the control (d\xa0=\xa0‒0.71) and at 60 min for the JFJ group (d\xa0=\xa0‒0.60). For control, cortisol increased to higher than the baseline at 30 and 60 min (d = 0.54 and d\xa0=\xa00.76, respectively). For the JFJ group, the cortisol levels were significantly higher than the baseline at 30 min (P\xa0=\xa00.022). Performance during sprints was higher in the JFJ group than in the control (P\xa0=\xa00.002). In the control group, performance was with both IL-6 (semipartial correlation; sr\xa0=\xa0-0.59, large effect size) and cortisol at 0 h (sr\xa0=\xa0-0.52, large effect size).\n\n\nCONCLUSIONS\nJFJ intake attenuated the antiinflammatory response to HIIE, possibly resulting from a lower degree of muscle stress.