Photodynamic therapy in vulvar lymphangioma: Case report.

Abstract

The aim of this case report was to evaluate the treatment of vulvar lymphangioma applying photodynamic therapy (PDT). Patient aged 61 years old complained of burning, local pain, which caused intense discomfort for over 5 years. She had developed vulvar edema, papules and vesicles that draining clear exudate, in which histological finding confirmed the vulvar lymphangioma. A red diode laser (Photon Lase III, DMC, Brazil) was applied locally after a 2% methylene blue aqueous solution (MB) in the vulvar target area. It was used a 660\u2009nm wavelength light source, irradiance- 100\u2009mW/cm2, radiant energy-20\u2009J/cm2, exposer time-40 seconds, applied weekly at 10 points onto vulvar area in a total of 5 sessions. A clinical improvement post PDT was observed as well as a better quality of life. Post 3 years follow up no recurrence was observed. The clinical response followed MB- mediated PDT suggested a non-invasive, secure and low-cost treatment.