Physics and Imaging in Radiation Oncology | 2019
Integration of biological factors in the treatment plan evaluation in breast cancer radiotherapy
Abstract
Highlights • This study suggests a PQM methodology for breast cancer radiotherapy evaluation.• The risk/benefit balance estimation includes tumor biology and smoking status.• Smoking status influenced risk/benefit balance for different treatment techniques.• Survival benefit dominated for all patients with high-risk breast cancer.• Survival benefit for smokers with low- or intermediate- risk cancer was not seen.