[Concordances and predictors of biopsies in renal tumors].

Abstract

AIM\nEvaluate the concordance between the renal lesions biopsy s histology and the final histology of the surgical specimen according to histological subtype, and search for predictive factors of non-concordance.\n\n\nMATERIAL\nWe performed a monocentric retrospective study that included 156 patients suffering from a renal tumor that benefited a lesion biopsy before surgical treatment. Sensibility and specificity of the renal lesion s biopsy for histological diagnostic of the different renal tumors where calculated.\n\n\nRESULTS\nOne hundred and fifty-eight renal tumor biopsies were realized between 2001 and 2016. One hundred and forty-three renal cell carcinoma were found on the surgical piece, 135 were diagnosed on prior biopsy. Global concordance rate was 88%. For the establishment of the nuclear Fuhrmann grade, the concordance rate (low vs. high grade) was 72.9%. The cohort was divided into 2 groups according to the existence (group 1, n=139) or the absence (group 2, n=19) of concordance. Group 1 and 2 differed by the predominance of men in group 1 (66% vs. 37%, P=0.013), distance between the sinus and the tumor above 4mm (65% vs. 42%, P=0.05).\n\n\nCONCLUSION\nIn renal tumor care, renal biopsy is a reliable testing. However, some factors most likely linked to the tumor anatomy (intra-sinusal tumor) and their histological composition were involved in the lack of non-contribution to the diagnosis.\n\n\nLEVEL OF EVIDENCE\n4.