Association of raised blood lead levels in pregnant women with preeclampsia: A study at tertiary centre.

Abstract

OBJECTIVE\nThis study aims to find the blood lead levels in pregnant women and its association with pre-eclampsia.\n\n\nMATERIAL AND METHODS\nThe study included 44 healthy pregnant females and 23 pre-eclamptic women. Demographic data and common risk factors for lead toxicity were recorded including age, residence, occupation, husband occupation, passive smoking, use of cosmetics, kajal, surma, receiving supplements/vitamins, history of house remodelling, plumbing, source of potable water, paint in house, use of lead-glazed ceramic and pica. Venous blood was collected and lead level was determined by atomic absorption spectrometry.\n\n\nRESULTS\nThe mean blood lead level was 2.38\xa0±\xa02.43 ug/dL in controls and 3.42\xa0±\xa02.18 ug/dL in preeclamptic women which was significantly higher (p\xa0=\xa00.0132). Strong correlation of BLL was observed with blood pressure in pre-eclamptic women. Pre-eclamptic patients were observed to be at increased risk of being lead exposed in terms of occupation and living conditions.\n\n\nCONCLUSION\nHigher blood lead level is associated with increased risk of preeclampsia. Patients should be counselled for lifestyle modification to prevent complications.