Urogynecological survey in a group of Italian women treated for overactive bladder: Symptoms and quality of life analysis during the Covid-19 period

Abstract

\n Objectives\n The aim of this study is to assess the impact of life change and social distancing measures, during the Covid-19 outbreak, on the OAB symptoms and quality of life in women underwent different types of treatment.\n \n Materials and methods\n Observational survey analysis in OAB treated patients was performed. The women showed a greater than 50% improvement during specific therapy for OAB. Population had previously completed bladder diary, OAB-Q symptom, OAB HRQL scale, SF-36 and PGI-I questionnaires. Four weeks after the introduction of the restrictive measures, these women were invited to complete the same questionnaires by e-mail for new evaluation during Covid-19 outbreak. Primary endpoint was changes in number of voids/24h, urgent micturitions/24h, urinary incontinence events/24h, nocturia events. Secondary endpoints were the assessment of the change in the OAB-SF, SF-36 questionnaires and PGI-I satisfaction.\n \n Results\n Six hundred seventy-three patients were considered. The mean age was 63.21\xa0±\xa010.24 years. Four weeks after the start of the social distancing measures, the increase in mean number of voids/24h (7.13\xa0±\xa01.08 vs 9.76\xa0±\xa02.12, p\xa0<\xa00.0001), urgent micturition episodes/24h (2.65\xa0±\xa01.11 vs 4.57\xa0±\xa01.28, p\xa0<\xa00.0001), nocturia episodes (1.19\xa0±\xa01.21 vs 2.83\xa0±\xa00.94, p\xa0<\xa00.0001) was observed. The OAB symptom scores (32.67\xa0±\xa012.88 vs 51.23\xa0±\xa012.11, p\xa0<\xa00.0001), OAB-HRQL (75.45\xa0±\xa012.76 vs 48.23\xa0±\xa010.34, p\xa0<\xa00.0001), and SF-36 (82.15\xa0±\xa011.78 vs 69.39\xa0±\xa010.85, p\xa0<\xa00.0001) changed significantly. The satisfaction decreased significantly at the PGI-I during the Covid-19 period 79.8% vs 45% (p\xa0<\xa00.0001).\n \n Conclusions\n The Covid-19 outbreak and the restrictive social distancing measures have negatively influenced the OAB symptoms and quality of life in women underwent different types of treatment.\n