Emerging Brominated Flame Retardants 2-Ethylhexyl-2,3,4,5-tetrabromobenzoate (EHTBB) and Bis(2-ethylhexyl)-tetrabromophthalate (BEH-TEBP) in Chinese Food and Their Health Implications.

Abstract

2-Ethylhexyl-2,3,4,5-tetrabromobenzoate (EHTBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP) have been frequently detected in the environment, whereas studies in food are scare. The European Food Safety Authority has requested data for their risk assessment. Herein, dietary exposure and hazard quotient (HQ) were studied based on the 5th (2009-2012) and 6th (2015-2018) Chinese total diet studies (TDSs). EHTBB was found in 61.1 and 75.9% of the two TDS sample sets, respectively. The concentrations of EHTBB in animal-derived food were higher than those in plant-derived food. The estimated daily intakes (EDIs) were 1.33 and 0.97 ng/kg bw/day, and vegetables contributed to 48.5 and 39.2% of the EDIs based on the 5th and 6th TDS, respectively. The dietary exposure to EHTBB was similar to that to hexabromocyclododecane, brominated diphenyl ether-209, and tetrabromobisphenol A (TBBPA). The HQ for EHTBB was similar to that for decabromodiphenyl ethane and surpassed that for TBBPA. Therefore, EHTBB warrants further study in food.