Copper-catalyzed efficient access to 2,4,6-triphenyl pyridines via oxidative decarboxylative coupling of aryl acetic acids with oxime acetates

Abstract

A simple and efficient strategy for the synthesis of 2,4,6- triphenyl pyridines has been developed through copper-catalysed oxidative decarboxylative coupling of C(sp3) aryl acetic acids with oxime acetates using oxygen as a sole terminal oxidant.