Brønsted acid and Lewis acid co-promoted cascade cyclization reaction and application to the total synthesis of Erysotramidine

Abstract

A strategy for the syntheses of pyrrolo [2,1-a] isoquinolines and indolizinoindolones via a Brønsted acid and Lewis acid co-promoted cascade reaction has been developed. The strategy was exemplified in the total synthesis of Erysotramidine.