Organic Chemistry Frontiers | 2021
Asymmetric synthesis of oxazolines bearing α-stereocenters through radical addition–enantioselective protonation enabled by cooperative catalysis
Abstract
An efficient radical conjugate addition/enantioselective protonation process was developed for the asymmetric synthesis of chiral oxazolines bearing an α-stereocenter through cooperative photoredox catalysis and asymmetric organocatalysis.