A Randomized Crossover Comparison of Airway Sealing with the Laryngeal Mask Airway Ambu AuraFlex at Three Intracuff Pressures in Pediatric Laparoscopic Surgery.

Abstract

OBJECTIVE\n\u2003An adequate intracuff pressure is important to ensure sufficient sealing function when using supraglottic airway devices to protect the airway from secretions and achieve adequate positive pressure ventilation. The aim of this study is to analyze a feasible and effective alternative Ambu AuraFlex intracuff pressure in child s laparoscopic surgery.\n\n\nSTUDY DESIGN\n\u2003Seventy-two children were included in this study. After insertion of the laryngeal mask airway AuraFlex, oropharyngeal leak pressure (OLP) was measured at intracuff pressures of 10, 30, and 60-cmH2O according to one of six sequences produced on the basis of 3\u2009×\u20096 Williams crossover design. During the intraoperative period, AuraFlex was maintained using the last intracuff pressure of the allocated sequence. Oropharyngeal leak pressure, peak airway pressure, the fiberoptic view, mucosal change, and complications were assessed at three intracuff pressures.\n\n\nRESULTS\n\u2003The OLP at the intracuff pressure of 10\u2009cmH2O was significantly lower than that of 30\u2009cmH2O (2# 18.1\u2009±\u20091.5 vs. 19.5\u2009±\u20091.4\u2009cmH2O, p\u2009=\u20090.001; 2.5# 17.7\u2009±\u20091.2 vs. 20.2\u2009±\u20091.4, p\u2009=\u20090.001) and 60\u2009cmH2O (2# 18.1\u2009±\u20091.5 vs. 20.0\u2009±\u20091.3\u2009cmH2O, p\u2009=\u20090.002; 2.5# 17.7\u2009±\u20091.2 vs. 20.8\u2009±\u20091.1, p\u2009=\u20090.003). Compared with the peak airway pressure in pre-and postpneumoperitoneum, the OLP was significantly higher. Subgroup analysis showed no differences in mucosal change and complications.\n\n\nCONCLUSION\n\u2003Intracuff pressures of 30 may be sufficient for the Ambu AuraFlex in child s laparoscopic surgery, and there may be no added benefit of an intracuff pressure of 60\u2009cmH2O, as oropharyngeal leak pressures were similar.