Epidemiology of Dupuytren disease and Patients Undergoing Selective Fasciectomy

Abstract

Objective \u2003To describe the epidemiological and clinical profile of patients with Dupuytren disease treated by selective fasciectomy and the factors associated with the severity of the disease. Methods \u2003Retrospective descriptive observational study involving 247 patients with Dupuytren disease, from 2013 to 2019. Multivariate logistic regression was performed for data analysis. Results \u2003Most patients were male (83.8%), self-declared white (65.2%), alcoholics (59.6%) and 49% were smokers, with a mean age of 66\u2009±\u20099 years old, with 77.2% presenting symptoms of the disease after the age of 51 years old. Approximately 51.9, 29.6 and 17.3%, respectively, had arterial hypertension, diabetes mellitus and dyslipidemia comorbidities. Bilateral involvement of the hands was observed in 73.3% of the patients. The rate of intra- and post-selective fasciectomy complications was of 0.6 and 24.3%, respectively, with 5.2% of the patients needing reintervention after 1 year of follow-up. After multivariate analysis, males were associated with bilateral involvement of the hands (odds ratio [OR]\u2009=\u20092.10; 95% confidence interval [CI]: 1.03–4.31) and with a greater number of affected rays (OR\u2009=\u20093.41; 95% CI: 1.66–7.03). Dyslipidemia was associated with reintervention (OR\u2009=\u20095.7; 95% CI\u2009=\u20091.03–31.4) and bilaterality with a higher number of complications (35.7 versus 19.7%). Conclusion \u2003A low rate of reintervention and operative complications was observed in patients with Dupuytren disease treated by selective fasciectomy. Male gender was associated with severe disease (bilaterality and more than two affected rays), and dyslipidemia with reintervention.