The Journal of asthma : official journal of the Association for the Care of Asthma | 2021
Mental health indices may fully mediate the relationship between morningness-eveningness and disease control among adult asthma patients.
Abstract
The aim of this study was to assess the association between mornigness-eveningness and disease control with consideration of mental state as a mediator and the control of confounding factors among adult asthma patients. This is a cross-sectional study, which included a non-random sample of N\u2009=\u200966 patients from an outpatient unit with a confirmed asthma diagnosis, who gave an informed consent and completed a set of questionnaires: a survey comprising questions about sociodemographic and clinical characteristics, the Asthma Control Test (ACT), the Composite Scale of Morningness (CSM), and the General Health Questionnaire (GHQ-28). Mediation models were created separately for each GHQ-28 dimension (somatic symptoms, anxiety/insomnia, social dysfunction and depressive symptoms), for a total score and for four GHQ-28 dimensions together, considered as mediators. Low morning affect was related to poor disease symptom control among patients with asthma. The effect was fully mediated by non-psychotic mental health indices. Evening-time preference was associated with a rise in asthma control, and mediated by somatic symptoms and anxiety/insomnia, when controlled for morning affect. The current study underlines the significance of assessment of both individual morningness-eveningness preference and mental health in the management of asthma symptoms.