Polycyclic Aromatic Compounds | 2019
Synthesis and Molecular Modeling Studies on Novel C2 Alkylated Benzoazonine Scaffold and Corresponding 2-Pyrazoline Derivatives as Acetylcholinestrase Enzyme Inhibitors
Abstract
A rapid and efficient methodology was performed for the synthesis of α,β-unsaturated ketones 2a–k containing benzoazonine core through Claisen-Schmidt reaction of the benzoazonine-2,7-dione 1 and v...