Effects of two modalities of noninvasive ventilation on breathing pattern of very low birth weight preterm infants immediately after extubation: a quasi-experimental study.

Abstract

AIM\nThe primary objective of this study was to investigate the effects of two modalities of noninvasive ventilation, continuous positive airway pressure-CPAP and non-synchronized nasal intermittent positive pressure ventilation-nsNIPPV, on breathing pattern of very low birth weight preterm infants immediately after extubation.\n\n\nMETHODS\nIt was conducted a quasi-experimental study at a public university hospital. Infants with gestacional age ≤32\u2009weeks and birth weight ≤1,500\u2009g were randomized into the sequences, prior extubation: CPAP - nsNIPPV (1) or nsNIPPV - CPAP (2). Each preterm infant was studied for a period of 60\u2009min in each ventilatory mode. Respiratory inductive plethysmography was used to assess breathing pattern. Inferential analysis was performed by repeated measures ANOVA or Friedman test.\n\n\nRESULTS\nEleven preterm infants were studied and a total of 7,564 respiratory cycles were analyzed. No significant differences were observed in any of the comparisons made for any of the breathing pattern variables (p\u2009>\u2009.05).\n\n\nCONCLUSIONS\nThere was no significant difference on breathing pattern between CPAP and nsNIPPV of preterm infants after extubation.