Human challenge trials to assess the efficacy of currently approved COVID-19 vaccines against SARS-CoV-2 variants

Abstract

Human challenge trials to assess the efficacy of currently approved COVID-19 vaccines against SARS-CoV-2 variants Shan Su, Yiming Shao and Shibo Jiang Key Laboratory of Medical Molecular Virology (MOE/MOH/CAM), School of Basic Medical Sciences, Shanghai Institute of Infectious Diseases and Biosecurity, Fudan University, Shanghai, People’s Republic of China; State Key Laboratory of Infectious Disease Prevention and Control (SKLID), National Center for AIDS/STD Control and Prevention (NCAIDS), Chinese Center for Disease Control and Prevention (China CDC), Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, People’s Republic of China