A state-informed stimulation approach with real-time estimation of the instantaneous phase of neural oscillations by a Kalman filter.

Abstract

OBJECTIVE\nWe propose a novel method to estimate the instantaneous oscillatory phase to implement a real-time system for state-informed sensory stimulation in electroencephalography (EEG) experiments.\n\n\nAPPROACH\nThe method uses Kalman filter-based prediction to estimate current and future EEG signals. We tested the performance of our method in a real-time situation.\n\n\nMAIN RESULTS\nOur method showed higher accuracy in predicting the EEG phase than the conventional autoregressive model-based method.\n\n\nSIGNIFICANCE\nA Kalman filter allows us to easily estimate the instantaneous phase of EEG oscillations based on the automatically estimated autoregressive model implemented in a real-time signal processing machine. The proposed method has a potential for versatile applications targeting the modulation of EEG phase dynamics and the plasticity of brain networks in relation to perceptual or cognitive functions.