Technology for increasing the bioavailability of feed using quorum sensing inhibitors

Abstract

The article presents the results of studies on increasing the bioavailability of feed, when using oak bark extract (OBE) and quorum sensing inhibitors (QSI) in the diet of cattle, in particular, the effect on volatile fatty acids, pH, ammonia and the content of nitrogen metabolites. The use of OBE and QSI was accompanied by an increase in the concentration of VFAs by 1.17 and 5.56 % (P≤0.05) three hours after feeding. The studies revealed an increase in the concentration of ammonia in the cicatricial content when adding ECD and IR by up to 2.88 and 8.80 % (P≤0.001) 3 hours after feeding, respectively. The same tendency is observed at a 6-hour exposure, the ammonia level increases by 6.08 % (P≤0.01) and 11.08 % (P≤0.001). The effect of oak bark extract on the bioavailability of the forage substrate in the rumen was accompanied by an increase in the total nitrogen content by 2.10% (P≤0.05), and in the group using quorum inhibitors, by 4.41% (P≤0.01). 6 hours after feeding, the content of non-protein nitrogen decreased by 4.56 and 7.45 % (P≤0.01) in the OBE and QSI groups; this indicates a significant rate of nitrogen assimilation by the scar microbiota which converts it into protein.