Effect of mackerel (Rastrelliger) arsik soup on the LDL levels of hypercholesterolemic rats

Abstract

Fish arsik soup is a popular traditional food in North Sumatera especially in Batak ethnic. This research aimed to evaluate the effects of different dose of mackerel fish arsik soup on body weight and LDL blood level in rats that were given a cholesterol rich feed namely quail egg yolk. Research was performed by using a Randomized Group Design. Forty male rats were grouped into 5 groups. The first group (K1) was the negative control group which was given distilled water and basal diet. The second, third, and fourth groups were given fish arsik soup with the dose of 1 ml/200 g body weight (bw)/day (K2), 2 ml/200 g bw/day (K3), and 3 ml/200 g bw/day (K4), and the last group was positive control group which was given gemfibrozil (K5). The result shows that rats fed quail egg yolk had a state of body weight gain and hypercholesterolemic. Administration of mackerel fish arsik soup to hypercholesterolemic rats with various dose had significantly (p<0.05) lower LDL level of rat blood compared to negative and positive control groups. The administration of mackerel fish arsik soup 1 ml/200 g bw/day resulted in the highest reduction in LDL levels in the rat’s blood.