914\u2003A Comparison of Mortality, Indicators of Treatment Success and Complications of Resuscitative Endovascular Balloon Occlusion of Aorta (REBOA): A Systematic Review and Meta-Analysis

Abstract

\n \n \n This study aims to provide an updated review on in-hospital mortality rates in patients who underwent Resuscitative Endovascular Balloon Occlusion of Aorta (REBOA) versus Resuscitative thoracotomy (RT) or standard care without REBOA, to identify potential indicators of REBOA use and complications.\n \n \n \n Cochrane and PRISMA guidelines were used to perform the study. A literature search was done from 01 January 2005 to 30 June 2020 using EMBASE, MEDLINE and COCHRANE databases. Meta-analysis was conducted using a random effects model and the DerSimonian and Laird estimation method.\n \n \n \n 25 studies were included in this study. The odds of in-hospital mortality of patients who underwent REBOA compared to RT was 0.18 (p\u2009<\u20090.01). The odds of in-hospital survival of patients who underwent REBOA compared to non-REBOA was 1.28 (p\u2009=\u20090.62). There was a significant difference found between survivors and non-survivors in terms of their pre-REBOA systolic blood pressure (SBP) (19.26\u2009mmHg, p\u2009<\u20090.01), post-REBOA SBP (20.73\u2009mmHg, p\u2009<\u20090.01), duration of aortic occlusion (-40.57 mins, p\u2009<\u20090.01) and ISS (-8.50, p\u2009<\u20090.01). Common complications of REBOA included acute kidney injury, multi-organ dysfunction and thrombosis.\n \n \n \n Our study demonstrated lower in-hospital mortality of REBOA versus RT. Prospective multi-centre studies are needed for further evaluation of the indications, feasibility, and complications of REBOA.\n