Brain | 2019

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis



Radioligands targeting the 18 kDa translocator protein (TSPO) are increasingly used to visualise inflammation in the brain. Nutma et al. report that TSPO expression in multiple sclerosis lesions originates mainly from astrocytes and microglia, but is not restricted to cells with a specific pro-inflammatory phenotype.

Volume 142
Pages 3440 - 3455
DOI 10.1093/BRAIN/AWZ287
Language English
Journal Brain

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