504 A Novel Hemostatic Agent Improves Split-Thickness Skin Graft Donor Site Healing

Abstract

We identified 10 patients who were admitted to a single, verified burn center for burn management between July and September of 2018. All patients underwent tangential excision and debridement of their partial-thickness or full-thickness burns. The study agent was placed directly on all donor sites. This was wrapped with a petroleum-based occlusive dressing with 3% bismuth tribromophenate and dry gauze dressing. The entire dressing was left in place for seven days postoperatively, after which it was removed for wound inspection. Split-thickness skin grafts create secondary wounds at donor sites. The optimal donor site dressing is not established. One novel agent, designed as a hemostatic, is made of etherified sodium carboxymethyl cellulose as a water-soluble, bioresorbable nanocellulose matrix. When the product contacts blood, it forms a gel that controls bleeding and may provide an optimal milieu for healing. We present a series of ten patients on whom this product was used as part of the donor site dressings.