Phosphomatics: interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets

Abstract

MOTIVATION\nMass spectrometry-based phosphoproteomics can routinely identify and quantify thousands of phosphorylated peptides from a single experiment. However interrogating possible upstream kinases and identifying key literature for phosphorylation sites is laborious and time-consuming.\n\n\nRESULTS\nHere, we present Phosphomatics - a publicly available web resource for interrogating phosphoproteomics data. Phosphomatics allows researchers to upload phosphoproteomics data and interrogate possible relationships from a substrate-, kinase-, or pathway-centric viewpoint.\n\n\nAVAILABILITY\nPhosphomatics is freely available via the internet at: https://phosphomatics.com.\n\n\nSUPPLEMENTARY INFORMATION\nSupplementary data are available at Bioinformatics online.