The epiGenomic Efficient Correlator (epiGeEC) tool allows fast comparison of user datasets with thousands of public epigenomic datasets

Abstract

Summary: In recent years, major initiatives such as the International Human Epigenome Consortium have generated thousands of high‐quality genome‐wide datasets for a large variety of assays and cell types. This data can be used as a reference to assess whether the signal from a user‐provided dataset corresponds to its expected experiment, as well as to help reveal unexpected biological associations. We have developed the epiGenomic Efficient Correlator (epiGeEC) tool to enable genome‐wide comparisons of very large numbers of datasets. A public Galaxy implementation of epiGeEC allows comparison of user datasets with thousands of public datasets in a few minutes. Availability and implementation: The source code is available at https://bitbucket.org/labjacquespe/epigeec and the Galaxy implementation at http://epigeec.genap.ca. Supplementary information: Supplementary data are available at Bioinformatics online.