Effects of Daily and Intermittent Intake of New Zealand Blackcurrant Extract on Cardiovascular Responses During Moderate Intensity Exercise in Males (P23-011-19).

Abstract

Objectives\nSeven-day intake of anthocyanin-rich New Zealand blackcurrant extract affected exercise-induced cardiovascular responses by vasodilation. It is not known whether daily intake of NZBC extract is required for effectiveness. Effects of daily and intermittent NZBC extract intake on cardiovascular responses were examined during brisk walking.\n\n\nMethods\nFifteen healthy men (mean\xa0±\xa0SD age: 24\xa0±\xa06 yr, body mass: 79\xa0±\xa016 kg, height: 178\xa0±\xa06 cm, BMI: 24.7\xa0±\xa04.3 kg·m-2, IPAQ score: 4534\xa0±\xa01576 MET·week-1) volunteered. Resting metabolic equivalent (1-MET) was measured using Douglas bags (1-MET: 3.97\xa0±\xa00.66 ml·kg-1·min-1) and an incremental walking test to determine the relationship between walking speed and MET. A randomised, cross-over (14-day washout) experimental design was used for baseline, 14-day intermittent (14I, every other day), and 14-day continuous (14C, daily) intake. Participants consumed 2 capsules of NZBC extract (600 mg and containing 210 mg of anthocyanins, CurraNZ™ Health Currancy Ltd., Surrey, UK) with breakfast. On the morning of testing, the final 2 capsules were ingested 2-hr before the 30-min brisk walk at 4 (n\xa0=\xa03) or 5 (n\xa0=\xa012) METs (walking speed: 5.68\xa0±\xa00.67 km·hr-1). Cardiovascular responses were measured at 7-10, 17-20 and 27-30 min during the walk by Portapres Model 2, averaged and analysed (ANOVA and post-hoc t-tests).\n\n\nResults\nThere were no changes in heart rate (e.g., baseline: 102\xa0±\xa018 beats·min-1), systolic blood pressure (e.g., baseline: 158\xa0±\xa018 mm Hg) and ejection time (e.g., baseline: 0.28\xa0±\xa00.03 s). Cardiac output (baseline: 11.7\xa0±\xa02.0, 14I: 12.5\xa0±\xa02.0, 14C: 12.7\xa0±\xa02.1 L·min-1, P\xa0=\xa00.009) and stroke volume (baseline: 114\xa0±\xa013, 14I: 123\xa0±\xa017, 14C: 126\xa0±\xa021 mL·min-1, P\xa0=\xa00.004) were higher, and total peripheral resistance (baseline 0.51\xa0±\xa00.11, 14I: 0.45\xa0±\xa00.09, 14C: 0.44\xa0±\xa00.12 mmHg·L-1·min-1, P\xa0=\xa00.001), diastolic blood pressure (baseline: 71\xa0±\xa09, 14I: 66\xa0±\xa09, 14C: 63\xa0±\xa011 mm Hg, P\xa0<\xa00.001) and mean arterial pressure (baseline 93\xa0±\xa010, 14I: 88\xa0±\xa09, 14C: 87\xa0±\xa011 mm Hg P\xa0=\xa00.006) were lower for 14I and 14C intake.\n\n\nConclusions\nDaily intake of anthocyanin-rich NZBC extract is not required to obtain beneficial cardiovascular responses during walking.\n\n\nFunding Sources\nHealth Currancy (UK) Ltd and CurraNZ (NZ) Ltd provided supplements and support for conference attendance with Blackcurrant New Zealand Inc. (NZ).