European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery | 2021
Comparison of uniportal video-assisted thoracoscopic versus thoracotomy bronchial sleeve lobectomy with pulmonary arterioplasty for centrally located non-small-cell lung cancer.
Abstract
OBJECTIVES\n\n\n\nMETHODS\nThis study aimed to investigate the efficacy of bronchial sleeve lobectomy with pulmonary arterioplasty by uniportal video-assisted thoracoscopic surgery (UniVATS) in centrally located non-small-cell lung cancer.\n\n\nRESULTS\nOne hundred and two thoracotomy and 31 UniVATS cases were included in this retrospective, single-centre study. Baseline characteristics, perioperative performance and survival outcomes were compared between the 2 groups.\n\n\nCONCLUSIONS\nCompared with the thoracotomy group, the UniVATS group was associated with lower postoperative blood transfusion rate (P\u2009=\u20090.043), decreased postoperative hospital stays (P\u2009=\u20090.008), shorter drainage duration (P\u2009=\u20090.003) and less drainage volume during the first postoperative 24\u2009h (P\u2009=\u20090.005). Besides, the 3-year overall survival and recurrence-free survival were comparable between the 2 groups (log-rank, P\u2009=\u20090.81 and P\u2009=\u20090.78, respectively). In addition, squamous cell carcinoma was proved to be the independent favourable predictor for overall survival [hazard ratio (HR) 0.44, 95% confidence interval (CI) 0.24-0.80; P\u2009=\u20090.008], and advanced pathological stage was found to be independently associated with worse overall survival (IIIB stage: HR 3.21, 95% CI 1.13-9.12; P\u2009=\u20090.028) and recurrence-free survival (IIIB stage: HR 3.54, 95% CI 1.32-9.51; P\u2009=\u20090.012).