MO848PREVALENCE OF COVID -19 IN CHRONIC HEMODIALYSIS PATIENTS AT THE TARIJA DEPARTAMENTAL HEMODIALYSIS CENTER DURING THE PEACK OF THE ANDEMIC JULY - SEPTEMBER 2020

Abstract

Abstract Background and Aims Bolivia was the last country to enter in the list of Latin American countries to report cases for the worldwide pandemic of COVID-19, reporting its first two confirmed cases on March 11, 2020 in the cities of Santa Cruz and Oruro. In Tarija department, the peak of cases was registered in the months of July, August and September. The Departmental Hemodialysis Center during this period had 71 registered patients undergoing chronic hemodialysis sessions. In this article we display the prevalence of patients who were infected with COVID-19 during that period of time. Method This is a prospective cohort observational study in which 71 patients were observed, who underwent hemodialysis sessions during the three shifts during the day (morning, afternoon and evening, during the months of July, August and September, months which were the peak of the pandemic in Tarija. Patients suspected of being transmitted with the disease, underwent immunochromatography IgM/IgG, ELISA anti SARS-CoV-2 and RT/PCR tests before confirming the diagnosis of COVID-19. Patients who had hemodialysis sessions for a period of less than 3 months were excluded from the study, and also those who changed their treatment modality for peritoneal dialysis to hemodialysis. Results 63 patients, 27 men and 36 women, who underwent hemodialysis sessions during the observational period met the inclusion criteria of the study. 7 patients were excluded for not meeting the inclusion criteria, 6 with a period less than 3 months undergoing hemodialysis and 1 patient who had changed the treatment modality from peritoneal dialysis to HD were excluded too. Of the 63 hemodialysis patients, 57 patients remained healthy and 6 were diagnosed with COVID-19 (Table 1). The prevalence of patients who presented COVID-19 in the hemodialysis center was 9%, with 33% of mortality and 83% who were able to recover and receive epidemiological discharge (figure 1). Of the 6 patients who developed COVID-19, 3 were women and 3 were men, 4 patients with previous hepatitis B infection who were dialyzed in the room with machines HBV + and 2 patients without liver infections who were dialyzed in negative machines. Three patients evolved asymptomatic during the SARS-CoV-2 infection, 2 presented thermal rises and mild cough, but without compromise in O2 saturation or ventilatory function, and one patient who died developed mild cough, slight fever and a hemodialysis catheter-related bloodstream infection by Staphylococcus aureus, confirmed in blood culture. Clinical characteristics of study participants (N=63) COVID negative N= 57 COVID positive N= 6 All patients N= 63 Age Mean 51.08 57,6 51.66 Gender F (m) % 58(42) 50(50) 57(43) Ethnicity Latin % 98 100 98 Black % 2 0 2 Reason of HD Diabetes nephropaty % 35 50 36 Hypertensive nephropaty % 25 0 22 GMN % 26 50 29 PKD % 5 0 5 Other % 9 0 8 Vintage on HD (m) mean 29 (3-108) 12 ( 6-18) (3-108) Conclusion The prevalence of patients infected by SARS-CoV-2 was 9% with a mortality of 17% (1 patient), validating that strict patient control and prevention measures become a great support to avoid massive spread between patient prone to acquire this infectious disease.