Abstract 7: Novel Stem Cell Model of Frontonasal Dysplasia derived from Pedigree with ALX1-Mutation

Abstract

PURPOSE: The availability of an objective outcome measure for facial reconstructive surgery remains elusive. Evaluations submitted by external raters or by patient selfreport may be influenced by expert knowledge, emotional antecedent, or implicit attitude. These types of subjective ratings, or objective measures such as anthropometric analysis, may unreliably convey how one is perceived by others. We are interested in observers’ instantaneous, reflexive responses to the human face, and how those instinctive responses relate to subjective judgment of a given face. We explored the visual markers that lead to differential perception of patients before and after facial reanimation surgery. By examining the early stages of visual processing that occur, we intended to measure changes in the focus of impression formation, thereby helping surgeons and their patients prioritize areas for reconstruction.