Drug News.

Abstract

www.Nursing2021.com January l Nursing2021 l 9 COVID-19 TREATMENTS WHO recommends against remdesivir use B ecause evidence of effectiveness is lacking, the World Health Organization (WHO) issued a conditional recommendation against the use of remdesivir to treat COVID-19 in hospitalized patients regardless of disease severity. The recommendation was developed by an international panel of experts tasked with developing guidelines that match scientific standards with the speed required to respond to an ongoing pandemic. In October, the WHO Solidarity Trial, an international clinical trial investigating effective treatments for COVID-19, published interim results. The panel reviewed these data as well as three other randomized controlled trials. In all, the panel considered data from over 7,000 patients across the four trials and concluded that remdesivir had no important effect on mortality, need for mechanical ventilation, time to clinical improvement, and other patientimportant outcomes. The panel called for more research, especially to provide higher certainty of evidence for specific patient groups, and encouraged continued enrollment in trials evaluating remdesivir.