The authors reply

Abstract

e1050 www.ccmjournal.org October 2021 • Volume 49 • Number 10 the simultaneous risk of thrombosis together with potentially fatal bleeding events (particularly if additional factors such as an extracorporeal circulation comes into play). Both the associated mortality and the long-term morbidity for thrombosis versus bleeding highlight the utmost importance of a tailored individualized approach to choose the right degree of anticoagulation.