Pancreas | 2019
A Systemic Inflammation Response Index Could be a Predictive Factor for mFOLFIRINOX in Metastatic Pancreatic Cancer
Abstract
No. patients 20 25 38 0.48 Age, mean (range), y 57 (23–67) 63 (35–72) 66 (48–79) 0.09 ECOG PS 0.003 0 17 (85) 13 (52) 16 (42) ≥1 3 (15) 12 (48) 22 (58) Sex 0.14 Male 14 (70) 18 (72) 20 (57) Female 6 (30) 7 (28) 18 (43) Comorbidities 0.41 Yes 17 (85) 21 (84) 27 (71) No 3 (15) 4 (16) 11 (29) Location 0.83 Head 10 (50) 16 (64) 19 (50) Body-tail 10 (50) 9 (36) 19 (50) Location metastases 0.59 Only liver 12 (60) 18 (72) 26 (68) Extrahepatic 1 (5) 3 (12) 4 (10) Liver + other sites 7 (35) 4 (16) 8 (22) CA 19-9 U/mL 0.65 <1000 11 (55) 11 (44) 18 (47) ≥1000 9 (45) 14 (56) 20 (53) Presence of biliary stent 0.16 Yes 9 (45) 8 (32) 16 (42) No 11 (55) 17 (68) 19 (58) Median OS, mo 11.5 7 4 0.01