ABO Blood Group and the Risk of Pancreatic Neoplasms in Chinese Han Population

Abstract

*P < 0.0001. P < 0.05. P ancreatic cancer is one of the most aggressive cancers. Accumulating epidemiological studies suggested a link between human blood group antigens and carcinogenesis or progression of various human tumors including pancreatic cancer. So far, there are few large studies of this kind in China. To understand more about the relationship between ABO blood group and the risk of developing pancreatic cancer, we collected data from pancreatic cancer patients of the Han Chinese people diagnosed in our institution between February 1, 2010, and May 31, 2017, and evaluated whether ABO blood type was a risk factor for pancreatic cancer. Meanwhile, we investigated whether there is a link between ABO blood group and pancreatic neuroendocrine tumors (pNETs) and other types of pancreatic masses. In addition, correlations betweenABOblood group and carbohydrate antigen (CA) 19-9, CA 125, and carcinoembryonic antigen (CEA) were also investigated. We included patients with definite pathological diagnosis and blood types. The