IUCrJ | 2021
Crystallographic models of SARS-CoV-2 3CLpro: in-depth assessment of structure quality and validation
Abstract
Over 100 models of SARS-CoV-2 3CLpro, a major drug-design target for COVID-19, have been carefully validated and assembled in a dedicated database. Their comparative analysis provides lessons for similar medically oriented efforts and for structural biology in general.