Intensity of SLX predicts distance of tumor spread through alveolar spaces in stage I lung adenocarcinoma

Abstract

Tumor spread through alveolar spaces (STAS) is a recently described invasive pattern associated with the prognosis and recurrence of lung adenocarcinoma. This study was performed to determine whether the presence and distance of STAS can be predicted by the immunohistochemical intensity of SLX, a well‐known cell adhesion protein.