Topiramate (Topamax) for Migraine Prophylaxis.

Abstract

The global prevalence of migraine headaches is estimated to be about 15%, consisting mostly of young and middle-aged adults.1 Migraine headaches not only cause a burden of pain and suffering, but also result in significant loss of productivity. For example, in the European Union migraines are estimated to cost nearly 50 billion Euros in lost productivity in terms of aggregate direct and indirect costs to society annually.2 A reliable method of preventing symptoms would be beneficial in terms of quality of life as well as societal productivity.3.