Deficits in frontoparietal activation and anterior insula functional connectivity during regulation of cognitive‐affective interference in bipolar disorder

Abstract

Bipolar disorders (BD) are characterized by emotion and cognitive dysregulation. Mapping deficits in the neurocircuitry of cognitive‐affective regulation allows for potential identification of intervention targets. This study used functional MRI data in BD patients and healthy controls during performance on a task requiring cognitive and inhibitory control superimposed on affective images, assessing cognitive and affective interference.