Longitudinal analysis of cognitive performances in recent‐onset and late‐life Bipolar Disorder: A systematic review and meta‐analysis

Abstract

Neurocognitive deficits have been widely reported in euthymic Bipolar Disorder (BD) patients and contribute to functional disability. However, the longitudinal trajectory of these deficits remains a subject of debate. Although most research to this date shows that neurocognitive deficits tend to be stable among middle‐age BD patients, it remains plausible that deterioration occurs at either early or late stages of this condition.