Network meta‐analyses of systemic treatments for psoriasis: a critical appraisal

Abstract

There are numerous systemic medications in use for psoriasis, with additional investigational agents being studied. However, head‐to‐head, randomized clinical trials are rare and cannot feasibly compare all treatments. A network meta‐analysis (NMA) synthesizes the available evidence to provide estimates for all pairwise comparisons. Here, we summarize and appraise two recent NMAs that assessed systemic therapies for moderate‐to‐severe psoriasis.