Kaposi sarcoma in HIV‐negative men who have sex with men: a case series of nonepidemic Kaposi sarcoma

Abstract

Kaposi sarcoma (KS) is an angioproliferative malignancy associated with human herpesvirus-8 (HHV-8). Four variants are classically described, distinguished by clinical course and populations affected1 . Epidemic or acquired immune deficiency syndrome (AIDS)-related KS is the most aggressive type and occurs in HIV-positive patients. Classic KS affects elderly men of eastern European or Mediterranean descent, while endemic KS affects younger adults and children in African countries. The iatrogenic variant arises in immunosuppressed patients, such as organ-transplant recipients.